Using Admixture
This is a tutorial on how to use Admixture, which is an ancestry inference tool.
Installations
Note: Jupyter notebook, R, and plink should already be installed in your conda environment at this point. If you do not, visit the pca and plotting tabs
Admixture:
conda install -c bioconda admixture
Using Admixture
Admixture is a fairly easy tool to use. The terminal command is as follows:
admixture <Bed File Path> K
- K is the number of theoretical source populations
- The BED file is combined to contain both query and reference datasets
Output
This will create two output files:
<File header>.Q file
: Contains the ancestry fractions for each individual<File header>.P file
: Contains the allele frequencies for each individual
The .Q.K file is generally the file of interest when looking to plot ancestry compositions for a given dataset.